Studies

We are continuously engaged in medical and clinical research to validate the effectiveness and functionality of Hilotherm devices. Some of our studies are available below

Post Operative Cooling Studies

3D evaluation of postoperative swelling using two different cooling methods following orthognathic surgery

3D evaluation of postoperative swelling in treatment of zygomatic bone fractures using 2 different cooling therapy methods

Post-operative pain reduction: meta-analysis of Hilotherapy verses conventional facial cooling

ACL Study Ruffilli

Comparative evaluation of the usability of 2 different methods to perform mild hypothermia in patients with out-of-hospital cardiac arrest

Hilotherm Efficacy in Controlling Postoperative Facial Edema in Patients Treated for Maxillomandibular Malformations

3D evaluation of postoperative swelling following third molar surgery using 2 different cooling therapy methods: a randomised observer blind prospective study

Evaluation of the Efficacy of Hilotherapy for Postoperative Edema, Ecchymosis, and Pain After Rhinoplasty

Development of swelling following orthognathic surgery at various cooling temperatures by means of hilotherapyea clinical, prospective, monocentric, single-blinded, randomised study

ChemoCare Studies

Prevention of taxane chemotherapy‑induced nail changes and peripheral neuropathy by application of extremity cooling: a prospective single‑centre study with intrapatient comparison

Cropsi study: Efficacy and safety of cryotherapy and cryocompression in the prevention of chemotherapy-induced peripheral neuropathy in patients with breast and gynecological cancer–A prospective, randomized trial

A randomized controlled trial of hand/foot-cooling by hilotherapy to prevent oxaliplatin-related peripheral neuropathy in patients with malignancies of the digestive system

Preventing taxane‑related peripheral neuropathy, pain and nail toxicity: a prospective self‑controlled trial comparing hilotherapy with frozen gloves in early breast cancer

Chemotherapy-induced neurotoxicity in the treatment of gynecological cancers: State of art and an innovative approach for prevention

CIPN-Prophylaxe: neues Thermoheilverfahren

Innovative Approach for the Prevention of Chemotherapy-Induced Peripheral Neuropathy in Cancer Patients: A Pilot Study With the Hilotherm Device, the Poliambulanza Hospital Experience